MCAO sutures for rodent stroke models. MCAO (middle cerebral artery occlusion) sutures for inducing ischemic stroke models in rats and mice.
MCAO sutures are silicone-rubber coated nylon monofilaments, in which the silicone-rubber coating is engineered for ensuring a complete occlusion of the middle cerebral artery (MCA) origin while avoiding subarachnoid hemorrhage (SAH). Doccol MCAO sutures have been well recognized and preferably selected by stroke investigators for inducing ischemic stroke models.
Using Doccol monofilaments for inducing MCAO models has been widely accepted as a necessary technical step and also a new standard for ensuring the highest quality of stroke modeling. MCAO sutures are available in nylon monofilament material USP size 3-0, 4-0, 5-0, 6-0, 7-0, and 8-0; diameters of silicone-rubber coated part range from 0.15 mm to 0.58 mm; coating lengths are available from 1.5 mm to 10 mm. Using Doccol monofilaments for inducing MCAO models has been reported to be able to drastically decrease the within-group variation of stroke models, reducing the standard deviation (SD) to 5% of the mean value for infarction volume. For more information please read Doccol Made a Difference in Stroke Modeling. Doccol also provides sorted MCAO sutures of different diameters and coating lengths (SSK series) for surgeons to find out their optimal MCAO sutures.
Doccol products are referred by over a thousand scholarly articles. Customer include top-ranked universities, highly prestigious research institutes, and world-leading pharmaceutical companies from all over the world.
MCAO sutures are available in nylon monofilament material USP size 3-0, 4-0, 5-0, 6-0, 7-0, and 8-0, which are categorized first by coating diameter, then further by coating length. We provide a match chart below to help you select coating diameters:
Animal Body |
Suggested |
Bare filament |
8-0, 7-0 |
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8-0, 7-0 |
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8-0, 7-0, 6-0 |
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8-0, 7-0, 6-0 |
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8-0, 7-0, 6-0 |
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5-0, 6-0 |
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5-0, 4-0 |
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5-0, 4-0 |
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5-0, 4-0 |
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4-0, 3-0 |
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4-0, 3-0 |
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4-0, 3-0 |
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3-0 |
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3-0 |
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3-0 |
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3-0 |
MCAO sutures for the following tip (coated part) diameters:
Note: The product is for lab research use only (RUO). Not for Human Use.
Feel free to ask Query