CASP3 Monoclonal Antibody

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Product Name Elabscience CASP3 Monoclonal Antibody
Catalog No. E-AB-22209
Pack Size 200uL/120uL/60uL
Brand Elabscience Bionovation Inc.
Product Detail CASP3 Monoclonal Antibody is a Mouse Monoclonal Antibody to CASP3 Monoclonal
Features
Host: Mouse

Application: IHC-p

Species reactivity: Human, Mouse, Rat

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide of Caspase-3

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Application: The product is for laboratory research use only. Not for any other use.

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.