Catenin beta Monoclonal Antibody

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Product Name Elabscience Catenin beta Monoclonal Antibody
Catalog No. E-AB-70230
Pack Size 200uL/120uL/60uL
Brand Elabscience Bionovation Inc.
Product Detail Catenin beta Monoclonal Antibody is a Mouse Monoclonal Antibody to Catenin beta Monoclonal
Features
Host: Mouse

Application: WB, IHC

Species reactivity: Human, Mouse, Rat

Concentration: 420 ug/mL

Immunogen: Recombinant protein corresponding to Mouse ?-catenin

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Application: The product is for laboratory research use only. Not for any other use.

CTNNB1,also known as ?-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .