Concentration: 0.77 mg/mL
Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD31
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Application: The product is for laboratory research use only. Not for any other use.
Platelet endothelial cell adhesion molecule-1 (PECAM-1,CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. It is highly expressed on the surface of the endothelium,making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets,monocytes,neutrophils,natural killer cells,megakaryocytes and some types of T-cell . As well as its role in cell-cell adhesion,PECAM-1 functions as a signaling receptor,and is involved in important physiological events such as nitric oxide production,regulation of T-cell immunity and tolerance,leukocyte transendothelial migration and inflammation and angiogenesis .
