Concentration: 2 mg/mL
Immunogen: Recombinant protein corresponding to Mouse Mac2
Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Application: The product is for laboratory research use only. Not for any other use.
Galectins are a family of animal lectins defined by shared characteristic amino-acid sequences and affinity for ?-galactose-containing oligosac-charides . Galectin-3 contains one carbohydrate recognition domain (CRD) and a proline- and glycine-rich N-terminal domain through which is able to form oligomers. Galectin-3 is widely expressed in many normal tissues and a variety of tumors. It is found intracellularly in nucleus and cytoplasm or secreted outside of cell,being present on the cell surface or in the extracellular space . Galectin-3 is involved in various biological processes including cell growth,adhesion,differentiation,apoptosis,angiogenesis,immune response,neoplastic transformation and metastasis .