NFKBIB Monoclonal Antibody

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Product Name Elabscience NFKBIB Monoclonal Antibody
Catalog No. E-AB-22175
Pack Size 200uL/120uL/60uL
Brand Elabscience Bionovation Inc.
Product Detail NFKBIB Monoclonal Antibody is a Mouse Monoclonal Antibody to NFKBIB Monoclonal
Features
Host: Mouse

Application: IHC-p

Species reactivity: Human, Mouse, Rat

Concentration: 1 mg/mL

Immunogen: Recombinant Protein

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Application: The product is for laboratory research use only. Not for any other use.

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.