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Product Information

  • Product Name Elabscience Recombinant APG5L Monoclonal Antibody
  • Catalog No. E-AB-81459
  • Pack Size 100uL/50uL/
  • Brand Elabscience Bionovation Inc.
  • Product Detail Recombinant APG5L Monoclonal Antibody is a RabbitRabbit Monoclonal Antibody to Recombinant APG5L Monoclonal
  • Features

    Host: Rabbit

    Application: WB, IF

    Species reactivity: Human, Mouse, Rat

Concentration: 300 ug/mL

Immunogen: A synthetic peptide of human APG5L/ATG5

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Application: The product is for laboratory research use only. Not for any other use.

ATG5,also named as APG5L and ASP,belongs to the ATG5 family. It is required for autophagy. It plays an important role in the apoptotic process,possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process,occurring downstream of caspase activity. Autophagy is a catabolic process for the autophagosomic-lysosomal degradation of bulk cytoplasmic contents. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. It mediates autophagosome-independent host protection.

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