Recombinant beta Catenin Monoclonal Antibody

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Product Name Elabscience Recombinant beta Catenin Monoclonal Antibody
Catalog No. E-AB-81445
Pack Size 100uL/50uL/
Brand Elabscience Bionovation Inc.
Product Detail Recombinant beta Catenin Monoclonal Antibody is a RabbitRabbit Monoclonal Antibody to Recombinant beta Catenin Monoclonal
Features
Host: Rabbit

Application: WB, IHC-P

Species reactivity: Human, Mouse, Rat, Hamster

Concentration: 300 ug/mL

Immunogen: A synthetic peptide of human beta Catenin

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Application: The product is for laboratory research use only. Not for any other use.

CTNNB1,also known as ?-Catenin,is an evolutionarily conserved,multifunctional intracellular protein. CTNNB1 was originally identified in cell adherens junctions (Ajs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the Ajs,CTNNB1 is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. Deregulation of CTNNB1 activity is associated with multiple diseases including cancers. .