Recombinant c Myc Monoclonal Antibody

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Product Name Elabscience Recombinant c Myc Monoclonal Antibody
Catalog No. E-AB-81443
Pack Size 100uL/50uL/
Brand Elabscience Bionovation Inc.
Product Detail Recombinant c Myc Monoclonal Antibody is a RabbitRabbit Monoclonal Antibody to Recombinant c Myc Monoclonal
Features
Host: Rabbit

Application: WB

Species reactivity: Human, Mouse, Rat

Concentration: 300 ug/mL

Immunogen: A synthetic peptide of human c-Myc

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Application: The product is for laboratory research use only. Not for any other use.

This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.