Recombinant Cofilin Monoclonal Antibody

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Product Name Elabscience Recombinant Cofilin Monoclonal Antibody
Catalog No. E-AB-81548
Pack Size 100uL/50uL/
Brand Elabscience Bionovation Inc.
Product Detail Recombinant Cofilin Monoclonal Antibody is a RabbitRabbit Monoclonal Antibody to Recombinant Cofilin Monoclonal
Features
Host: Rabbit

Application: WB, IHC-P, IF

Species reactivity: Human

Concentration: 300 ug/mL

Immunogen: A synthetic peptide of human Cofilin

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Application: The product is for laboratory research use only. Not for any other use.

Cofilin is a ubiquitous actin-binding protein required for the reorganization of actin filaments. It is a member of ADF (actin-depolymerizing factor)/cofilin family that is a key regulator of actin dynamics and essential for cellular motility,cytokinesis,and endocytosis. Cofilin activity is tightly regulated by phosphorylation and dephosphorylation. Phosphorylation at Ser3 can inhibit its activity,also causing translocation from the nucleus to the cytoplasm.