Recombinant PERK Monoclonal Antibody

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Product Name Elabscience Recombinant PERK Monoclonal Antibody
Catalog No. E-AB-81482
Pack Size 100uL/50uL/
Brand Elabscience Bionovation Inc.
Product Detail Recombinant PERK Monoclonal Antibody is a RabbitRabbit Monoclonal Antibody to Recombinant PERK Monoclonal
Features
Host: Rabbit

Application: WB

Species reactivity: Human, Mouse, Rat

Concentration: 300 ug/mL

Immunogen: Recombinant protein of human PERK

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Application: The product is for laboratory research use only. Not for any other use.

The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome.