Recombinant PI3 Kinase p85 alpha Monoclonal Antibody

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Product Name Elabscience Recombinant PI3 Kinase p85 alpha Monoclonal Antibody
Catalog No. E-AB-81435
Pack Size 100uL/50uL/
Brand Elabscience Bionovation Inc.
Product Detail Recombinant PI3 Kinase p85 alpha Monoclonal Antibody is a RabbitRabbit Monoclonal Antibody to Recombinant PI3 Kinase p85 alpha Monoclonal
Features
Host: Rabbit

Application: WB, IF

Species reactivity: Human, Rat, Hamster

Concentration: 300 ug/mL

Immunogen: A synthetic peptide of human PI 3 Kinase p85 alpha

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Application: The product is for laboratory research use only. Not for any other use.

Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer,which is composed of a P110 catalytic subunit and a P85 regulatory subunit,is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.