Concentration: 300 ug/mL
Immunogen: A synthetic peptide of human Prohibitin
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Application: The product is for laboratory research use only. Not for any other use.
Prohibitin,also known as PHB,a member of the Band-7 family of proteins,is widely distributed in bacteria,plants,yeast,protozoa and mammals and is important in cell proliferation,differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria,where it acts as a chaperone protein,and is also found in the nucleus,where it negatively regulates transcription . Recent study confirmed that the expression and distribution of PHB,which is a nuclear matrix protein,affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .
