Recombinant SF3B1 Monoclonal Antibody

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Product Name Elabscience Recombinant SF3B1 Monoclonal Antibody
Catalog No. E-AB-81510
Pack Size 100uL/50uL/
Brand Elabscience Bionovation Inc.
Product Detail Recombinant SF3B1 Monoclonal Antibody is a RabbitRabbit Monoclonal Antibody to Recombinant SF3B1 Monoclonal
Features
Host: Rabbit

Application: WB, IHC-P

Species reactivity: Human, Mouse, Hamster

Concentration: 300 ug/mL

Immunogen: A synthetic peptide of human SF3B1

Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

Application: The product is for laboratory research use only. Not for any other use.

This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.