XRCC4 Monoclonal Antibody

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Product Name Elabscience XRCC4 Monoclonal Antibody
Catalog No. E-AB-22044
Pack Size 200uL/120uL/60uL
Brand Elabscience Bionovation Inc.
Product Detail XRCC4 Monoclonal Antibody is a Mouse Monoclonal Antibody to XRCC4 Monoclonal
Features
Host: Mouse

Application: WB, IHC-p, IF, IP

Species reactivity: Human

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Application: The product is for laboratory research use only. Not for any other use.

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.